The government confronts mysterious incidents that threaten international safety and determines it must employ a team of experts who are shrunken to microscopic size to infiltrate and combat otherwise impenetrable dangers; thus is the Combined Miniature Defense Force created; it is led by US Navy Commander Jonathan Kidd, an expert frogman; Guru, a Tibetan wizard possessing fantastic powers; Erica Lane, an astronaut, doctor, and biologist; and Busby Birdwell, a scientist and engineer who builds the CMDF's primary aerial craft, the Voyager.